Best Practices for Technical Writing in Regulatory Submissions: INDs, NDAs, and PMAs

Charles H. Paul
Instructor: Charles H. Paul
Date: Tuesday April 29, 2025
Time:

10:00 AM PDT | 01:00 PM EDT

Duration: 60 Minutes
Webinar Id: 606456

Price Details

Live Webinar
$150. One Attendee
$290. Unlimited Attendees
Recorded Webinar
$190. One Attendee
$390. Unlimited Attendees
Combo Offers   (Live + Recorded)
$289 $340   One Attendee
$599 $680   Unlimited Attendees

Unlimited Attendees: Any number of participants

Recorded Version: Unlimited viewing for 6 months (Access information will be emailed 24 hours after the completion of live webinar)

Overview:

Effective technical writing is critical for successful regulatory submissions, including Investigational New Drug (IND) applications, New Drug Applications (NDA), and Premarket Approval (PMA) submissions.

This webinar will explore best practices for crafting clear, concise, and compliant regulatory documents that meet FDA and ICH guidelines. Attendees will learn strategies for structuring submissions, maintaining consistency across documents, and presenting complex data effectively through tables and figures. The session will also cover common pitfalls in regulatory writing, the importance of plain language principles, and techniques for improving document readability. Additionally, participants will gain insights into collaboration with cross-functional teams, version control, and the regulatory review process to ensure high-quality, submission-ready documents.

Why you should Attend:

Participants in this training will gain valuable insights into the essential principles of technical writing for regulatory submissions, ensuring their documents meet the stringent requirements of the FDA and other regulatory agencies. This session will equip attendees with best practices for structuring Investigational New Drug (IND), New Drug Application (NDA), and Premarket Approval (PMA) submissions in a clear, concise, and compliant manner.

They will learn techniques to improve readability, maintain consistency across sections, and present complex scientific data effectively. Additionally, the training will provide strategies for effective collaboration with cross-functional teams, managing version control, and navigating the regulatory review process. By enhancing their technical writing skills, participants will improve the quality of their submissions, reduce the risk of delays, and increase the likelihood of regulatory approval.

Areas Covered in the Session:

  • Introduction (5 min)
    • Welcome and objectives
      • Importance of technical writing in regulatory submissions
      • Key regulatory submissions: IND (Investigational New Drug), NDA (New Drug Application), PMA (Premarket Approval)
      • What attendees will learn
  • Overview of Regulatory Submissions (10 min)
    • Introduction to IND, NDA, and PMA
      • Purpose and requirements of each submission type
      • Key regulatory agencies: FDA (U.S.), EMA (Europe), other global bodies
    • Common Challenges in Regulatory Writing
      • Complexity and volume of data
      • Need for clarity, consistency, and compliance
      • Meeting FDA and ICH guidelines
  • Best Practices for Clear and Concise Technical Writing (15 min)
    • Regulatory Style and Tone
      • Writing for reviewers: Concise, objective, and structured
      • Avoiding ambiguity and unnecessary jargon
    • Document Structure and Formatting
      • Standardized templates and section headings (eCTD structure)
      • Logical flow and organization
    • Grammar, Readability, and Plain Language
      • Using active vs. passive voice
      • Simplifying complex technical concepts
      • Best tools for readability (e.g., readability scores, plain language principles)
    • Use of Tables, Figures, and Appendices
      • How to present complex data effectively
      • Labeling and referencing best practices
  • Regulatory Expectations and Compliance Considerations (10 min)
    • Key FDA and ICH Guidelines Impacting Writing
      • FDA Guidance for Industry: IND, NDA, and PMA-specific expectations
      • ICH M4: Common Technical Document (CTD) structure
    • Consistency and Traceability of Data
      • Ensuring alignment between different submission sections
      • Managing cross-references and hyperlinks in electronic submissions
    • Common Pitfalls and How to Avoid Them
      • Overly technical language
      • Redundancy and contradictions
      • Poorly structured arguments and missing justifications
  • Strategies for Effective Collaboration in Regulatory Writing (10 min)
    • Cross-functional teamwork
      • Working with SMEs, regulatory affairs, and quality teams
    • Version Control and Document Management
      • Best practices for tracking changes and maintaining consistency
      • Utilizing document management systems
    • Review and Editing Process
      • Internal vs. external reviews
      • FDA’s expectations for well-structured submissions

Who Will Benefit:

  • Regulatory Affairs Professionals
  • Medical Writers
  • Quality Assurance Specialists
  • Clinical Research Associates
  • Pharmacovigilance Professionals
  • Research and Development Scientists
  • Technical Documentation Specialists
  • Compliance Officers
  • Product Development Managers
  • Manufacturing and Quality Control Personnel
  • Submission Coordinators
  • Project Managers in Regulatory Affairs
  • Medical and Scientific Affairs Teams
  • Regulatory Consultants
  • Legal and Compliance Teams in Life Sciences

Speaker Profile
Charles H. Paul is the President of C. H. Paul Consulting, Inc. – a regulatory, manufacturing, training, and technical documentation consulting firm – celebrating its twentieth year in business in 2017. Charles has been a regulatory and management consultant and an Instructional Technologist for 30 years and has published numerous white papers on various regulatory and training subjects. The firm works with both domestic and international clients designing solutions for complex training and documentation issues.

He has held senior positions in consulting and in corporate training development prior to forming C. H. Paul Consulting, Inc.. He also worked for several years in government contracting managing the development of significant Army-wide training development contracts impacting virtually all of the active Army and changing the training paradigm throughout the military.

He has dedicated his entire professional career explaining the benefits of performance-based training

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